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Phagemid

    A '''phagemid''' is a type of cloning genetics|genetics Vector (biology)|vector developed as a coinfection of the M13 phage|M13 helper phage and plasmids to produce a smaller version of the virus an example is PRS314 which is of 478 kb size
    They find their application at phage displays
    A phagemid is different than a closely related cloning vector called a cosmid While a cosmid can enter a host cell very effectively almost all all of the genes have been removed to make room for exoginous DNA therefore the virus cannot replicate itself In a phagemid however an origin of replication is present This means that in the presence of a 'helper' virus such as f1, the rest of the genes to replicate viral proteins are present therefore more virus particles can be created using the host cells resources